Yigeng Tian,1,* Mingfeng Xia,2,* Shuai Zhang,3 Zhen Fu,4 Qingbin Wen,2 Feng Liu,4 Zongzhen Xu,4 Tao Li,4 Hu Tian4 1Department of Physics, School of Physics and Technology, University of VESTS URBAN Jinan, Jinan, Shandong, People’s Republic of China; 2Department of Surgery, Shandong University of Traditional Chinese Medicine, Jinan, Shandong,
Abstract Background Cisplatin (DDP) is an efficacious and widely applied chemotherapeutic drug for cervical cancer patients who are diagnosed as metastatic and inoperable, or desiring fertility preservation.Tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) selectively triggers cancer cells apoptosis by binding to cognate death r
The universal dihydrouridine (D) epitranscriptomic mark results from a reduction of uridine by the Dus family of NADPH-dependent reductases and is typically found within the eponym D-loop of tRNAs.Despite its apparent simplicity, D is structurally unique, with the Horse Shampoo potential to deeply affect the RNA backbone and many, if not all, RNA-c
Deep cortical lacerations with or without urinary extravasations have traditionally been managed by exploration and surgical repair.With improved and readily available radiologic imaging modalities like computed tomography and intravenous pyelography, we propose that the majority of these injuries can be followed expectantly with delayed interventi